The Dietary Supplements Health and Education Act (DSHEA) in 1994 was made possible through the collaboration of the Federal Trade Commission (FTC) and the Food and Drug Administration (FDA). The FDA is primarily responsible for claims on product labeling including the packaging, inserts and other materials while the FTC handles claims in advertising whether print, infomercials, catalogs and other similar direct marketing materials.

The act changed significantly FDA’s role in regulating the supplement labeling. It put emphasis that advertising especially on dietary supplements should be truthful, substantiated and not misleading.